FAQ
Warhead Hunter FAQ
Common questions about ligand solvent exposure mapping, candidate site inspection, and how Warhead Hunter fits into structure-guided medicinal chemistry workflows.
Artifacts
PDB / SDF / CSV Viewer files, manifests, and bundlesWhat does Warhead Hunter do?
Warhead Hunter maps atom-level solvent exposure on protein-bound ligands and helps researchers inspect candidate atoms for warhead installation, linker attachment, chemical expansion, and PROTAC-oriented design.
Does Warhead Hunter predict the best attachment site?
No. Warhead Hunter supports candidate modification-site inspection in structural context, but it does not guarantee the optimal site for synthesis, potency, or degrader performance.
What inputs are typically used?
A typical automated workflow uses a target name, a structure-search query, and an optional FASTA sequence. Manual upload workflows can use prepared SASA, mapping, metadata, scaffold, and structure files.
What kinds of outputs does the platform provide?
The repository and browser workflow support CSV, SVG, SDF, PDB, HTML, and manifest-style outputs that help users inspect exposure values and retrieve prepared result artifacts.
Need More Than A Quick Answer?
Move into the workflow guide, science background, or API docs when you want a deeper view of how the output should be used.